interface graph thumbnail
legend  pdf

structure nameHUMAN TFIIB-RELATED FACTOR 2 (BRF2) AND TBP BOUND TO U6#2 PROMOTER
(TRANSCRIPTION FACTOR IIIB 50 KDA SUBUNIT)
referenceGuthertz et al. 'Cell(Cambridge,Mass.)' 163 1375 2015
sourceHOMO SAPIENS
experimentX-ray (resolution=1.90, R-factor=0.187)
structural superfamilyCyclin-like;
multimeric complexes4roc_AB 4rod_AB 4roe_AB 5n9g_AC 5n9g_FH
redundant complexes4rod_A 4roe_A 5n9g
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureARY

Estimated binding specificities ?

contactlogo
# IC=4.007 IC/col=0.250 n_of_columns=16 specificity:   
A |   0   0  24  24  24  24  24  24  24  24  24  24  24   9   9  11
C |   0   0  24  24  24  24  24  24  24  24  24  24  24  11   9   9
G |  96  96  24  24  24  24  24  24  24  24  24  24  24  67   9  67
T |   0   0  24  24  24  24  24  24  24  24  24  24  24   9  69   9
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --ACRC------------YC------   L                      +------------4roc_A    
                                             +--------1 
  QT------------------EG----           +-----2        +------------6f40_V    
                                       !     ! 
  ----------------------VCTC         +-3     +---------------------7nvu_M    
                                     ! ! 
  ------------RG--YG--------       +-4 +---------------------------1qbj_C    
                                   ! ! 
  ------SGRGPTSGRG----------   L --5 +----------------------------7bhy_A    
                                   ! 
  ------------RC--YG--------       +----------------------------2acj_B    
                                 

home
updated Thu Dec 22 20:43:16 2022