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structure nameCRYSTAL STRUCTURE OF KLEBSIELLA PNEUMONIAE RSTA DNA-BINDING DOMAIN IN COMPLEX WITH RSTA BOX
(DNA-binding transcriptional regulator RstA)
referenceHsiao et al. 'Nucleic 42 8777 2014
sourceKlebsiella pneumoniae
experimentX-ray (resolution=2.70, R-factor=0.222)
structural superfamilyC-terminal effector domain of the bipartite response regulators;
sequence familyTranscriptional regulatory protein, C ter;
multimeric complexes4nhj_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRDVSRR

Estimated binding specificities ?

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# IC=8.756 IC/col=0.973 n_of_columns=9 specificity:   
A |   0   0   0  96   0  96  13  16   6
C |   0   0   8   0  96   0  13   6  78
G |   0  96   6   0   0   0  16  13   6
T |  96   0  82   0   0   0  54  61   6
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: RSTA CRYSTAL STRUCTURE OF KLEBSIELLA PNEUMONIAE RSTA DNA-BINDING DOMAIN IN COMPLEX WITH RSTA BOX mining
AAAATTGTACAPubMed4nhj_A(5.40e-06), 4nhj_AB(1.04e-02)
TACATNTNGTTACAPubMed4nhj_AB(9.43e-06)
TGTACAATTTTPubMed4nhj_A(5.40e-06), 4nhj_AB(1.04e-02)

Dendrogram of similar interfaces ?

matrix format
  
  --------RG----DTVT--STRG--WT--   L      +-------------------------6lxn_A    
                                          ! 
  --------RCTT----TTHTLA--------   L   +--5 +-----------------------7e1b_B    
                                       !  ! ! 
  ------------------------RG----       !  +-4                     +-4wcg_A    
                                       !    !       +-------------1 
  --RA--ST--ECTT--RAKA------HT--     --6    +-------2             +-7oz3_B    
                                       !            ! 
  --ETNTSCRGHC----RT--------QA--       !            +---------------5d4s_B    
                                       ! 
  --------NTVC--ECSTYTSTYC--RA--   L   !       +--------------------5ed4_A    
                                       +-------3 
  QA--------------------------NG               +--------------------7k63_U    
                                     

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updated Tue Dec 19 09:09:26 2023