interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA TRANSCRIPTIONAL REGULATOR PA2196 BOUND TO ITS OPERATOR DNA
(Transcriptional regulator)
referenceChoe et al. Biochem.Biophys.Res.Commun. 440 317 2013
sourcePseudomonas aeruginosa
experimentX-ray (resolution=2.90, R-factor=0.200)
structural superfamilyTetracyclin repressor-like, C-terminal domain;Homeodomain-like;
sequence familyBacterial regulatory proteins, tetR family;
multimeric complexes4l62_ABCD 4l62_EFGH 4l62_IJKL 4l62_MNOP
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureLKSYH

Estimated binding specificities ?

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# IC=3.678 IC/col=0.613 n_of_columns=6 specificity:   
A |   9   0   9  24  66  81
C |   7   0  73  24   7   1
G |  73   0   7  24   9   7
T |   7  96   7  24  14   7
scan!

Dendrogram of similar interfaces ?

matrix format
  
  LG----KG--STYTHT   L                   +-4l62_M    
                                         ! 
  LC--RTPTPTSTYT--   L     +-------------3   +6nsn_B    
                           !             ! +-1 
  ----TTRG----YTWA   L     !             +-2 +7jnp_A    
                         +-6               ! 
  VT--AGDT--TTYTLA   L   ! !               +5gpc_B    
                         ! ! 
  ----TCKGAG--YTHA     --7 +---------------5k7z_A    
                         ! 
  LTRG--PTAC--YT--   L   !       +---------3lsr_A    
                         !   +---4 
  ----TGKG----YCFA   L   +---5   +---------4pxi_B    
                             ! 
  MTRGTGPT--ATYTWT   L       +-------------5yej_B    
                       

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updated Tue Dec 19 09:04:42 2023