interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF A HYPERACTIVE MUTANT OF RESPONSE REGULATOR KDPE COMPLEXED TO ITS PROMOTER DNA
(KDP operon transcriptional regulatory protein KdpE)
referenceNarayanan et al. 'Nat 5 3282 2014
sourceEscherichia coli
experimentX-ray (resolution=2.53, R-factor=0.208)
structural superfamilyCheY-like;
sequence familyResponse regulator receiver domain; Transcriptional regulatory protein, C te;
multimeric complexes4kfc_AB 4kny_AB
redundant complexes4kny_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHRIY

Estimated binding specificities ?

contactlogo
# IC=4.007 IC/col=0.801 n_of_columns=5 specificity:   
A |   0   9  11  96  67
C |   0   9   9   0   9
G |   0  69   9   0  11
T |  96   9  67   0   9
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --------------------RG--DTVT--STRGWT   L               +---------------------6lxn_A    
                                                 +-------2 
  ------------------------------YGRG--           !       !                   +-4wcg_A    
                                               +-3       +-------------------1 
  --------------RC--------------------         ! !                           +-6l9z_S    
                                             +-4 ! 
  ------------TA----------------------       ! ! +-----------------------------4p0p_A    
                                           --5 ! 
  ----------------LGTAKGTA--HTRG------   L   ! +-----------------------------6jhe_A    
                                             ! 
  FTDTITVTATLG------------------------   L   +-----------------------------3zh2_C    
                                           

home
updated Tue Dec 19 09:03:25 2023