interface graph thumbnail
legend  pdf

structure nameTCAR-SSDNA COMPLEX CRYSTAL STRUCTURE REVEALS THE NOVEL SSDNA BINDING MECHANISM OF THE MARR FAMILY PROTEINS
(TcaR transcription regulator)
referenceChen et al. 'Nucleic 42 5314 2014
sourceStaphylococcus epidermidis
experimentX-ray (resolution=3.60, R-factor=0.274)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyMarR family;
multimeric complexes4kdp_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSEKRRK

Estimated binding specificities ?

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# IC=3.101 IC/col=0.620 n_of_columns=5 specificity:   
A |   0  24  13  96  16
C |  96  24  54   0  13
G |   0  24  13   0  54
T |   0  24  16   0  13
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ET--RGTCTGSTRG----KT   L           +-----------------------------6q2b_B    
                                   +-1 
  --TT--PTTCSTNT----RT   L       +-2 +-----------------------------4lln_I    
                                 ! ! 
  NGLTKTPTSTTT----RTRT   L     +-3 +-----------------------------7el3_B    
                               ! ! 
  --DCSA--TATT----RTRA   L   +-4 +-----------------------------1z9c_A    
                             ! ! 
  LTNTHG--RTYTPT----RT   L --5 +-----------------------------6qil_A    
                             ! 
  --------------YGRG--       +-----------------------------4wcg_A    
                           

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updated Tue Dec 19 09:03:20 2023