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structure nameTCAR-SSDNA COMPLEX CRYSTAL STRUCTURE REVEALS THE NOVEL SSDNA BINDING MECHANISM OF THE MARR FAMILY PROTEINS
(TCAR TRANSCRIPTION REGULATOR)
referenceY.M.CHANG et al. NUCLEIC ACIDS RES. V. 42 5314 2014
sourceSTAPHYLOCOCCUS EPIDERMIDIS
experimentX-ray (resolution=3.60, R-factor=0.274)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyMarR family;
multimeric complexes4kdp_AB
links to other resourcesPDBSum NPIDB BIPA PDIdb DNAproDB
protein sequence
interface signatureSEKRRK

Estimated binding specificities ?

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# IC=3.101 IC/col=0.620 n_of_columns=5 specificity:   
A |   0  24  13  96  13
C |  96  24  54   0  13
G |   0  24  13   0  54
T |   0  24  16   0  16
scan!

Dendrogram of similar interfaces ?

matrix format
  
  NT--KTPTQGSCNTKA--------RT----   L                                    +5bmz_B    
                                                                     +--1 
  --ET--RGTCTGSTRG------KT------   L                         +-------4  +6q2b_B    
                                                             !       ! 
  ------SANCTGTTPT------RT------   L                         !       +---5hlg_E    
                                                          +--8 
  ----TCLA--TCTTTT------RT------   L                      !  !          +6jbx_A    
                                                          !  !   +------3 
  ----LTRTPTNAVT--------RT------   L                      !  +---7      +6c2s_C    
                                                          !      ! 
  ----STPTATATTTKG--------------   L                +-----9      +-------5yi2_J    
                                                    !     ! 
  ----TT--PTTCSTNT------RT------   L                !     !             +4lln_I    
                                                    !     !        +----2 
  ----DCSA--TATT----RT--RA------   L             +-10     +--------5    +1z9c_A    
                                                 !  !              ! 
  --------ST--STHG------RA------   L             !  !              +-----3zpl_B    
                                          +-----11  !  
  ----------------YGRG----------          !      !  +--------------------4wcg_A    
                                          !      !  
  TT------KATTQTTGLTRTKA----FTYT   L   +-12      !               +------2p7c_B    
                                       !  !      +---------------6 
  ----------------YG------------       !  !                      +------4lb5_B    
                                     -13  !  
  --LTNTHG--RTYTPT------RT------   L   !  +-----------------------------6qil_A    
                                       !  
  ----TTRG--ATSTQT--RG----------   L   +-----------------------------5clv_J    
                                     

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updated Wed Jul 7 19:06:12 2021