interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF MS6564-DNA COMPLEX
(Transcriptional regulator, TetR family)
referenceYang et al. J.Biol.Chem. 288 23687 2013
sourceMycobacterium smegmatis
experimentX-ray (resolution=2.50, R-factor=0.224)
structural superfamilyHomeodomain-like;Tetracyclin repressor-like, C-terminal domain;
sequence familyBacterial regulatory proteins, tetR family;
multimeric complexes4jl3_ABCD
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureREKQTYR

Estimated binding specificities ?

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# IC=6.080 IC/col=0.608 n_of_columns=10 specificity:   
A |  78  78  24   6  24  24   6  96   0   6
C |   6   6  24  78  24  24   6   0  96   6
G |   6   6  24   6  24  24  78   0   0  78
T |   6   6  24   6  24  24   6   0   0   6
scan!

Dendrogram of similar interfaces ?

matrix format
  
  VT--AGDT--TTYTLA   L                     +5gpc_B    
                                         +-1 
  ----TTRG----YTWA   L   +---------------2 +7jnp_A    
                         !               ! 
  LC--RTPTPTSTYT--   L   !               +6nsn_B    
                       --6 
  MTRGTGPT--ATYTWT   L   !            +----5yej_B    
                         ! +----------3 
  MTRGAAVT--TTYT--   L   ! !          +----5fmp_B    
                         +-5 
  LTRG--PTAC--YT--   L     !     +---------3lsr_A    
                           +-----4 
  ----TGKG----YCFA   L           +---------4pxi_B    
                       

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updated Tue Dec 19 09:02:27 2023