interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF ADPNP-BOUND ADDAB WITH A FORKED DNA SUBSTRATE
(ATP-DEPENDENT HELICASENUCLEASE SUBUNIT A)
referenceKrajewski et al. Nature 508 416 2014
sourceBACILLUS SUBTILIS SUBSP. SUBTILIS STR. 168
experimentX-ray (resolution=2.80, R-factor=0.198)
structural superfamilyP-loop containing nucleoside triphosphate hydrolases;Restriction endonuclease-like;
sequence familyUvrD/REP helicase;
multimeric complexes3u44_AB 3u4q_AB 4ceh_AB 4cei_AB 4cej_AB
redundant complexes4ceh 3u44 4cej 3u4q
reference complex3u4q_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHIDQERFFRRHND

Estimated binding specificities ?

contactlogo
# IC=9.764 IC/col=0.362 n_of_columns=27 specificity:   
A |   0  13  24  24  24  24  24  24  24  13   0  24  24  24  24  24  24  24  24  24  24  24   0   0   0   0   0
C |   0  54  24  24  24  24  24  24  24  54   0  24  24  24  24  24  24  24  24  24  24  24   0   0   0   0   0
G |  96  13  24  24  24  24  24  24  24  13   0  24  24  24  24  24  24  24  24  24  24  24   0   0  96   0   0
T |   0  16  24  24  24  24  24  24  24  16  96  24  24  24  24  24  24  24  24  24  24  24  96  96   0  96  96
scan!

Dendrogram of similar interfaces ?

matrix format
  
  FG--RTHG----------LT--FT----------WTRGRT----HTST--------   L      +------------------------6ppr_B    
                                                                    ! 
  ------HT--------------FT----------FTRTRTNTATHT--ET----ET          !                         +4c2u_D    
                                                                    !                       +-1 
  ------HT--------------FT----------WTRTRT----HT----ET----       +--7               +-------2 +3pjr_A    
                                                                 !  !               !       ! 
  FT----HT--------------FT----------FTRTRT--ACHT--ET------       !  !     +---------4       +4c2t_B    
                                                                 !  !     !         ! 
  ------HTDTKTRTATFTLT--FT----------WTRTRT----HT----------   L   !  +-----6         +--------1uaa_B    
                                                               --8        ! 
  FT----HT------------STFT----------WGRTRT----HG----RTEGEG       !        !            +-----2is6_B    
                                                                 !        +------------3 
  FTTT--HT--------------FTDT----YT--WTRTRT----------------   L   !                     +-----2pjr_A    
                                                                 ! 
  --------------------------DTVT--PT----FT----HT----------   L   !        +------------------3upu_A    
                                                                 +--------5 
  --------------------------------VT------RT--HT----------   L            +------------------7otj_B    
                                                               

home
updated Mon Dec 18 09:54:03 2023