interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN OF ADPA, THE GLOBAL TRANSCRIPTIONAL FACTOR, IN COMPLEX WITH A TARGET DNA
(ADPA)
referenceMiyazono et al. J.Biol.Chem. 288 31019 2013
sourceSTREPTOMYCES GRISEUS
experimentX-ray (resolution=2.95, R-factor=0.238)
structural superfamilyHomeodomain-like;
sequence familyBacterial regulatory helixturnhelix protei;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSRRTDR

Estimated binding specificities ?

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# IC=4.090 IC/col=0.682 n_of_columns=6 specificity:   
A |  16   4   3  12   0  78
C |  45  81   3  60  96   6
G |  19   4  85  12   0   6
T |  16   7   5  12   0   6
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: ADPA
TGGCGGGTTCPubMed3w6v_A(6.84e-05)

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updated Tue Dec 19 08:23:21 2023