interface graph thumbnail
legend  pdf

structure nameHUMAN MUTSBETA COMPLEXED WITH AN IDL OF 3 BASES (LOOP3) AND ADP
(DNA MISMATCH REPAIR PROTEIN MSH2)
referenceNat.Struct.Mol.Biol. 19 72 2012 X-RAY DIFFRACTION
sourceHOMO SAPIENS
experimentX-ray (resolution=2.70, R-factor=0.212)
structural superfamilyDNA repair protein MutS, domain III;P-loop containing nucleoside triphosphate hydrolases;
sequence familyMutS domain V; MutS domain III; MutS family domain IV;
multimeric complexes2o8b_AB 2o8c_AB 2o8d_AB 2o8e_AB 2o8f_AB 3thw_AB 3thx_AB 3thy_AB 3thz_AB
redundant complexes2o8c_A 3thz_A 2o8b 2o8d 2o8e 2o8f 3thw 3thy
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  --DGFG------VGSG--                             +------3thx_A    
                                    +------------3 
  MGDAFGTTRCMC--PT--                !            +------1wb9_A    
                           +--------4 
  ----FGET----------       !        !               +----1ewq_A    
                           !        !             +-1 
  --YGKA------SAPA--     --5        +-------------2 +----3thx_B    
                           !                      ! 
  VCKCFGETMT----PG--       !                      +-----2o8b_B    
                           ! 
  ----------------RT       +----------------------------7jy6_F    
                         

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updated Thu Dec 22 19:34:50 2022