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structure nameSTRUCTURE OF CCPA-HPR-SER46P-ACKA2 COMPLEX
(CATABOLITE CONTROL PROTEIN A)
referenceSchumacher et al. 'Nucleic 39 2931 2011
sourceBACILLUS SUBTILIS
experimentX-ray (resolution=2.96, R-factor=0.216)
structural superfamilyPeriplasmic binding protein-like I;lambda repressor-like DNA-binding domains;
sequence familyBacterial regulatory proteins, lacI fami; Periplasmic binding proteins and sugar b;
multimeric complexes3oqm_AC 3oqn_AC 3oqo_AC
redundant complexes3oqn_A 3oqo_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIYSMASRNALA

Estimated binding specificities ?

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# IC=7.181 IC/col=1.026 n_of_columns=7 specificity:   
A |   0   0  57  13  96  96   0
C |   0   0  13  13   0   0  96
G |   0  96  13  13   0   0   0
T |  96   0  13  57   0   0   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: CCPA
ATAAAGCGTTTACAPubMed3oqm_AC(9.55e-03), 3oqn_AC(7.76e-08), 3oqo_AC(6.22e-04), ... (total=4)
ATAATTAATATAACAACAAAPubMed3oqm_C(7.60e-03)
TGTAAGCCCTAACAPubMed3oqm_AC(1.36e-03), 3oqn_AC(3.65e-13), 3oqo_AC(2.21e-04), ... (total=4)

Dendrogram of similar interfaces ?

matrix format
  
  IT--ST--ATTTSTRG----VTAGLCAC       +-----------------------------1rzr_C    
                                     ! 
  ITYTSGMTAA--STRG--NT--AGLCAT   L --3                             +3oqm_C    
                                     !            +----------------1 
  ----SG--TC------RG------LCKA   L   +------------2                +1jft_A    
                                                  ! 
  LT----ITTGTTST----DCIT--LCRT   L                +----------------7ce1_D    
                                   

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updated Tue Dec 19 07:57:53 2023