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legend  pdf

structure nameMOLECULAR BASIS OF ENGINEERED MEGANUCLEASE TARGETING OF THE ENDOGENOUS HUMAN RAG1 LOCUS
(V3E8K)
referenceSubramanian et al. 'Nucleic 39 729 2011
sourceCHLAMYDOMONAS REINHARDTII
experimentX-ray (resolution=2.30, R-factor=0.182)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes3mxb_AB 3mxb_RS
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSIQNNSRRYTYRVQKT

Estimated binding specificities ?

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# IC=11.491 IC/col=1.045 n_of_columns=11 specificity:   
A |   6  78   6   6   0   0  96   6   0   0  96
C |   6   6  72  78   0  96   0   6  96  96   0
G |   6   6  12   6   0   0   0  84   0   0   0
T |  78   6   6   6  96   0   0   0   0   0   0
scan!

Dendrogram of similar interfaces ?

matrix format



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updated Thu Dec 22 19:22:31 2022