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legend  pdf

structure nameDNA BINDING DOMAIN OF EARLY B-CELL FACTOR 1 (EBF1) BOUND TO DNA (CRYSTAL FORM II)
(Transcription factor COE1)
referenceGrosschedl et al. 'Genes 24 2270 2010
sourceMus musculus
experimentX-ray (resolution=2.40, R-factor=0.173)
multimeric complexes3mln_AB 3mlo_AB
redundant complexes3mlo_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSNRNANNNSK

Estimated binding specificities ?

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# IC=8.040 IC/col=0.618 n_of_columns=13 specificity:   
A |   0  24  24  24   0   0   0   0  85  64  24  24  64
C |  85  24  24  24   0   0   0   0   0  12  24  24  10
G |   1  24  24  24   0  96  96  96  11  10  24  24  12
T |  10  24  24  24  96   0   0   0   0  10  24  24  10
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RGSTNTRCNGATNA--NCNTSGKG   L                             +3mln_A    
                                 +-------------------------1 
  RGSTNTRCNCATNT--NCNTSGKG   L   !                         +3mlp_F    
                               --3 
  --------------RGATCT----   L   !                     +---3q05_D    
                                 +---------------------2 
  ----------------ATCT----                             +---3qyn_C    
                               

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updated Tue Dec 19 07:50:39 2023