3l2p_A : 3D-footprint complex

3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

Dendrogram of similar interfaces ?

matrix format

structure name	HUMAN DNA LIGASE III RECOGNIZES DNA ENDS BY DYNAMIC SWITCHING BETWEEN TWO DNA BOUND STATES (DNA ligase 3)
reference	Cotner-Gohara et al. Biochemistry 49 6165 2010
source	Homo sapiens
experiment	X-ray (resolution=3.00, R-factor=0.235)
structural superfamily	DNA ligase/mRNA capping enzyme, catalytic domain;Nucleic acid-binding proteins;
sequence family	ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal re; DNA ligase N terminus;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3l2p_A interface=25,305,505,506, hmrhkdcllrefrklcamvadnpsYntktqiiqdflrkggdvyltvklllpgviktvynlndkqivklfsrifncnpddmardleqgdvsetirvffeqsksfppaakslltiqevdefllrlskltkedeqqqalqdiasrctandlkciirlikhdlkmnsgakhvldaldpnayeafkasrnlqdvvervlhnaqevelsvqaslmtpvqpmlaeacksveyamkkcpngmfseikydgervqvhkngdhfsyfsrslkpvlphkvahfkdyipqafpgghsmildsevllidnktgkplpFgtlgvhkkaafqdanvclfvfdciyfndvslmdrplcerrkflhdnmveipnrimfsemkrvtkaldladmitrviqegleglvlkdvkgtyepgkrhwlkvkkdylnmadtadlvvlgafygqgskggmmsiflmgcydpgsqkwctvtkcagghddatlarlqneldmvkiskaavweitgaefskseahtadgisiRFprctrirddkdwksatnlpqlkelyqlsk

  
  YC--------------FT----------------------------RCFG--                                   +--3l2p_A    
                                                                                       +-1 
  ------------------KT------------------------ST--FG--                         +-------3 +--6bkg_A    
                                                                               !       ! 
  RT----HT----------RC--------KG--------------TT--FG--   L             +-------4       +---6p0c_A    
                                                                       !       ! 
  --------------------------------------------SA--FC--                 !       !       +---6rar_I    
                                                                    +--5       +-------2 
  --------------RA------------------------------FGLGIT              !  !               +---6dt1_A    
                                                               +----6  ! 
  ------------------------------------------------QT--         !    !  +-------------------6iml_A    
                                                             +-7    ! 
  ------------------LC--------KG--------------TA--FC--       ! !    +----------------------6gdr_A    
                                                           --8 ! 
  --YALA--RAKAIA------FA------------------------------       ! +---------------------------2hvr_B    
                                                             ! 
  ----------------------RTTTKT--TTATNTTTFTFTNT--------   L   +----------------------------6bhx_B

home
updated Tue Dec 19 07:47:41 2023