3ikt_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A REX-FAMILY REPRESSOR/DNA/NAD+ COMPLEX FROM THERMUS AQUATICUS (Redox-sensing transcriptional repressor rex)
reference	McLaughlin et al. Mol.Cell 38 563 2010
source	Thermus thermophilus HB27
experiment	X-ray (resolution=2.26, R-factor=0.234)
structural superfamily	NADP-binding Rossmann-fold domains;"Winged helix" DNA-binding domain;
sequence family	CoA binding domain; Putative DNAbinding protein Nterminu;
multimeric complexes	3ikt_AB 3il2_AB
redundant complexes	3il2_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3ikt_B interface=43,44,46,47,50,51,58, mkvpeaaisrlitylrileeleaqgvhrtsseqlgelaqvtaFQvRKdlSYfgsygtRgvgytvpvlkrelrhilglnrkwglcivgmgrlgsaladypgfgesfelrgffdvdpekvgrpvrggviehvdllpqrvpgrieialltvpreaaqkaadllvaagikgilnfapvvlevpkevavenvdflagltrlsfailnpkwr
interface signature	FQRKSYR

Estimated binding specificities ?

contact

# IC=7.140 IC/col=1.020 n_of_columns=7

specificity:

A |  13  13   0   0   0   0  96
C |  13  54   0   0   0   0   0
G |  57  16   0  96   0  96   0
T |  13  13  96   0  96   0   0

scan!

Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: Rex
TTCACAA	PubMed	3ikt_B(5.18e-05), 3ikt_AB(4.93e-03)
TTGTGAANNNNTTCACAA	PubMed	3ikt_B(4.94e-03), 3ikt_AB(6.49e-07)

Dendrogram of similar interfaces ?

matrix format

  
  FAQTRGKGSTYTRG--   L           +3ikt_B    
                         +-------1 
  SAQTRGQTNG--QT--   L   !       +3wgi_D    
                       --3 
  ATTTRGRGSTYTRA--   L   !       +3ket_A    
                         +-------2 
  SC--RGKGST--RAVA   L           +7wb3_B

home
updated Tue Dec 19 07:25:16 2023