2xro_E : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF TTGV IN COMPLEX WITH ITS DNA OPERATOR (HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGV)
reference	Gallegos et al. 'Genes 24 2556 2010
source	PSEUDOMONAS PUTIDA
experiment	X-ray (resolution=3.40, R-factor=0.217)
structural superfamily	GAF domain-like;"Winged helix" DNA-binding domain;
sequence family	IclR helixturnhelix domain; Bacterial transcriptional regulator;
multimeric complexes	2xro_ABEF
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2xro_E interface=22,33,34,35,37,38, qviaraasimralgshphglsLaaiaqlvglpRSTvQRiinaleeeflvealgpaggfrlgpalgqlinqaqtdilslvkpylrslaeeldesvslaslagdkiyvldrivserelrvvfpiginvpaaataagkvllaalpdetlqaalgeqlpvltsntlgrkalvkqlsevrqsgvasdldehidgvssfatlldtylgyyslaivmpssraskqsdlikkallqsklnieraigr
interface signature	LRSTQR

Estimated binding specificities ?

readout + contact

# IC=4.434 IC/col=0.887 n_of_columns=5

specificity:

A |   0   0  13  16  96
C |  96   0  13  13   0
G |   0  96  54  13   0
T |   0   0  16  54   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  LT----RTSGTG--QTRG------------------   L             +--------------------2xro_E    
                                                   +---5 
  ----------------RCYG----KT----------             !   !                    +2acj_B    
                                                   !   +--------------------1 
  --------TTHT----KG--------RC--------   L         !                        +7b0c_A    
                                               +---7 
  ------------------YGRG--------------         !   !                      +-4wcg_A    
                                               !   !       +--------------2 
  ETNTSCRGHC----RT----------QA--------         !   !  +----4              +-5d4s_B    
                                               !   !  !    ! 
  RC----------------------------------       +-8   +--6    +----------------7cow_T    
                                             ! !      ! 
  ----SGRGPT----SGRG------------------   L   ! !      +---------------------7bhy_A    
                                             ! ! 
  ----QTPTPG--TTRG--------------HT----   L --9 !                    +-------5xxp_A    
                                             ! +--------------------3 
  ----NTHG--RT--YTPT----------RT------   L   !                      +-------6qil_A    
                                             ! 
  ----------------IA----QC--------YART   L   +----------------------------1nk2_P

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updated Tue Dec 19 07:05:09 2023