interface graph thumbnail
legend  pdf

structure nameMOLECULAR BASIS OF ENGINEERED MEGANUCLEASE TARGETING OF THE ENDOGENOUS HUMAN RAG1 LOCUS
(I-CREI V2V3 VARIANT)
referenceChion-Sotine et al. 'Nucleic 39 729 2011
sourceCHLAMYDOMONAS REINHARDTII
experimentX-ray (resolution=2.31, R-factor=0.215)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes2xe0_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSIQKRSNQSATYSVDRSKT

Estimated binding specificities ?

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# IC=10.641 IC/col=0.887 n_of_columns=12 specificity:   
A |   3  87   3   3   3   0  87   0  24  75   0  96
C |   3   3  66  75   0   0   3   0  24   3  81   0
G |   3   3  12   3   3  96   3  96  24  15  15   0
T |  87   3  15  15  90   0   3   0  24   3   0   0
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Dendrogram of similar interfaces ?

matrix format



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updated Tue Dec 19 07:03:46 2023