| structure name | MOLECULAR BASIS OF HUMAN XPC GENE RECOGNITION AND CLEAVAGE BY ENGINEERED HOMING ENDONUCLEASE HETERODIMERS (DNA ENDONUCLEASE I-CREI) |
| reference | Cabaniols et al. Nature 456 107 2008 |
| source | CHLAMYDOMONAS REINHARDTII |
| experiment | X-ray (resolution=1.80, R-factor=0.149) |
| structural superfamily | Homing endonucleases; |
| sequence family | LAGLIDADG endonuclease; |
| multimeric complexes | 2vbj_AB 2vbl_AB 2vbn_AB 2vbo_AB |
| redundant complexes | 2vbj 2vbn 2vbo |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | SIQENSYRKKTRESVNKT |
Estimated binding specificities ?
| readout + contact |  |
A | 0 96 0 0 64 0 0 0 16 C | 0 0 0 0 16 0 96 96 16 G | 0 0 96 96 16 0 0 0 16 T | 96 0 0 0 0 96 0 0 48scan! |
Dendrogram of similar interfaces ?
matrix formatSTITQAKGRGSTNTQG--ST--ATTC----YT--SC----VCDTRG--ST--KGTG-- L +2xe0_B +-1 STITQANG--ST--RG--RG--YCTCYC--RG--------VCQT--------KGTC-- L +-2 +3mxb_R ! ! STITQAKGRGSTNTQT--ST--ATTC----YT--SC----VCDTRG--ST--KGTG-- L +----3 +3mxb_B ! ! SGIGQAKGNCSC--RG--QG--DGTAYC--AT--SC----VCKGRG--------TT-- L ! +6fb0_A +-12 SAIAQA----SC--RG--KG--QATAYC------ST----VA----------KTTT-- L ! ! +2vbl_B ! ! +-4 SAIAQAKG--ST--RG------QATAYC--RT--ST----VA--IT------KTTT-- L ! +----7 +2vbo_A ! ! SAYCLCITRGYA--QG--------IG--NA--RG--DT--IC--RG------------ L ! +2fld_B ! CCMT--ACSTAT--QA--YA--ICTART------KGRT--VAEC--QT---------- L +-13 +4yit_A ! ! +-5 ST--NAVTHGTCNAAT--LCYCECAT----YG--NADC--TCKTKG--SA-------- L ! ! +-8 +4lq0_A ! ! ! ! SA--RGRGNTKTSTST--EC--QGTA------ST------AT--KG------------ L ! ! +-9 +6bd0_A ! ! ! ! STIGRGRG----MCLT--EC--STKG----TTNA--------MGRT--SC-------- L +------------14 +-----10 +5t2n_A ! ! ! STMG------KGYCRT----RGVTSA----FCMC------STQTRG--EC-------- L ! ! ! +5esp_A ! ! +-6 --MGTASG----RAST--RGRGRG----------------DTRGRC--EC-------- L ! ! +6bce_A -15 ! SAIAQGKTNTSCYAQA------QATCYA--RG--RG--SAVA----------KGTC-- L ! ! +-1t9i_B ! +-----11 SANCSCKGLT--------DAECNATG----RC----------------DAQA----QC L ! +-2ex5_A ! --YTLT--------RGSGECRGVTTG----------------EARG--SC-------- L +----------------------2vs7_A |
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updated Tue Dec 19 06:58:41 2023