2v6e_B : 3D-footprint complex

structure name	PROTELOMERASE TELK COMPLEXED WITH SUBSTRATE DNA (PROTELEMORASE)
reference	Ellenberger et al. Mol.Cell 27 901 2007
source	KLEBSIELLA PHAGE PHIKO2
experiment	X-ray (resolution=3.20, R-factor=0.255)
multimeric complexes	2v6e_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2v6e_B interface=61,62,64,65,66,68,69,209,213,216,256,297,299,347,354,355,358,359,362,415,418,421,486,489,495,496, vkigelinslvseveaidasdrpqgdktkkikaaalkyknalfndkrkfrgkglekrisaNTfNSYmSRarkrfddrlhhnfeknviklsekyplyseelsswlsmpaasirqhmsrlqaklkeimplaedlsnikigtknseakinklankypewqfaisdlnsedwkdkrdylyklfqqgsslledlnnlkvnhevlyhlqlssaeRtsiQqrWanvlsekkrnvvvidyprymqaiydiinkpivsfdlttrRgmaplafalaalsgrrmieimlqgefsvagkytvtflgqaKkRsedkgisrkiytlcdatlfvslvnelrscpaaadfdevikgygendtRsengriNAilATafNpwvktflgddrrvykdsraiyariayemffrvdprwknvdedvffmeilghdDenTqlHykqfklanfsrtwrpnvgeenarlaalqkldsmmpdfargdagvrihetvkqlveqdpsikitnStlRpfnfsTRliprylefaadalgqfvgengqwqlkdeapaivlp
interface signature	NTNSYSRRQWRKRRNAATNDTHSRTR

Estimated binding specificities ?

readout + contact

# IC=15.696 IC/col=0.747 n_of_columns=21

specificity:

A |   3  96   0  84  24  24  24  24  24  11  24   7   1  96   0   0  77   0  96   0   0
C |  77   0  96   3  24  24  24  24  24  11  24  70  92   0   0   0   3   0   0  88   0
G |   3   0   0   6  24  24  24  24  24  63  24  11   3   0   0   0   7   0   0   7  89
T |  13   0   0   3  24  24  24  24  24  11  24   8   0   0  96  96   9  96   0   1   7

scan!

Dendrogram of similar interfaces ?

matrix format

  
  NTTTNTSAYTSTRT----RG--QCWT----RG--KA--RGRC----------NAAC----AATG----NT--DG--TG--HA--SG--RGTCRT--------   L                  +------------------2v6e_B    
                                                                                                                        +-----8 
  ------------------YA--RAKT--------KA--------IT------ST------RTLT----RT--DAEATT------------------------   L            !     !                  +4f43_A    
                                                                                                                        !     +------------------1 
  --------------TAAAYADA--KA----------------IT------ST------RTLT----RT----------------------------------   L            !                        +4e0p_A    
                                                                                                                     +-11  
  ----------------------------------------------------------YG--YAKT------------TT----------------------   L         !  !             +-----------5jk0_B    
                                                                                                                     !  !  +----------5 
  ----------------------------------------------ATVTDT------------RC------------------------------------   L      +-12  +-10          +-----------6en2_A    
                                                                                                                  !  !     !  
  ------------------------------------KT--------------------TT--STRGYC----------------------------------   L      !  !     +----------------------1z1b_B    
                                                                                                               +-13  !  
  --------------------------RAFC--------------------------NT----RGST----KT------------------------------   L   !  !  +--------------------------1flo_A    
                                                                                                               !  !  
  --------------------------------NC----------------------------TT--------------------------------------   L   !  +---------------------------2b9s_A    
                                                                                                               !  
  ------------------------------------------------------------------------------------------------YG----       !                           +-1sfu_A    
                                                                                                             -14              +------------4 
  ------------------------------------------------------------------------------------------------YG----       !              !            +-4lb5_B    
                                                                                                               !            +-6 
  ------------------------------------------------------------------------------------------------YG----       !            ! !              +2heo_D    
                                                                                                               !      +-----7 +--------------2 
  ----------------------------------------------------------------------------------------------RCYG--KT       !      !     !                +2acj_B    
                                                                                                               !      !     ! 
  ----------------------------------------------------------------------------------SG--QG--YCNC--------       +------9     +---------------2ve9_C    
                                                                                                                      ! 
  ----------------------------------------------------------------------------------------------RGYG----              !                   +-1qbj_C    
                                                                                                                      +-------------------3 
  ------------------------------------------------------------------------------------------------YGRG--                                  +-4wcg_A

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updated Tue Dec 19 06:58:01 2023