interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF UP1-TELOMERIC DNA COMPLEX
(PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1)
referenceHayashi et al. 'Genes 13 1102 1999
sourceHOMO SAPIENS
experimentX-ray (resolution=2.10, R-factor=0.195)
structural superfamilyRNA-binding domain, RBD;
sequence familyRNA recognition motif aka RRM, RBD, or;
reference complex1u1q_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureEQKFDVMFREKAVRSH

Estimated binding specificities ?

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# IC=6.969 IC/col=0.996 n_of_columns=7 specificity:   
A |   0  96   0   0  24   0  12
C |   0   0   0   0  24   0  12
G |   0   0  96  96  24   0  12
T |  96   0   0   0  24  96  60
scan!

Dendrogram of similar interfaces ?

matrix format
  
  EGQGKGFA----------DGVGMG------------FGRTETKTAGVA--RG--SGHA   L              +----------------2up1_A    
                                                                              ! 
  ----DGICLG--WG------QGKT--LT--KG--FGFGRG----PCNC----------   L   +----------3               +4y0f_A    
                                                                   !          !           +---1 
  ----RC----NU------------------KUNU--FC------PC------DC----       !          +-----------2   +3vaj_B    
                                                                 --4                      ! 
  ----TAFCSG----------LAKATG--TGSG--VGFA----RAEC--ACKC------   L   !                      +----5tkz_B    
                                                                   ! 
  --------------KGYG----------------------------------------   L   +---------------------------2ayg_A    
                                                                 

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updated Mon Dec 18 07:15:18 2023