interface graph thumbnail
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structure nameCRYSTAL STRUCTURE OF THE P22 C2 REPRESSOR PROTEIN IN COMPLEX WITH THE SYNTHETIC OPERATOR 9T
(Repressor protein C2)
referenceWilliams et al. Biochemistry 47 2325 2008
sourceEnterobacteria phage P22
experimentX-ray (resolution=1.53, R-factor=?)
structural superfamilylambda repressor-like DNA-binding domains;
sequence familyHelixturnhelix;
multimeric complexes2r1j_LR 3jxb_CD 3jxc_LR 3jxd_LR
redundant complexes3jxb_C 3jxc_R 3jxd_L
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQSNVASQRET

Estimated binding specificities ?

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# IC=4.007 IC/col=0.801 n_of_columns=5 specificity:   
A |   9   9  96  96   9
C |  11   9   0   0   9
G |   9   9   0   0  67
T |  67  69   0   0  11
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: C2
ATTAAAPubMed2r1j_L(3.56e-04), 3jxb_CD(5.34e-04), 3jxd_LR(3.47e-04), ... (total=6)

Dendrogram of similar interfaces ?

matrix format
  
  --QT--STNTVTATSTQTRTETTT----   L                        +2r1j_L    
                                                        +-1 
  ----ATATTTPTTTNT------------   L                +-----3 +6fix_D    
                                                  !     ! 
  ----RTTT--AT--STRG----TT----   L            +---5     +6chv_D    
                                              !   ! 
  RT--------RG----NT----ETRTYA   L   +--------6   +------7f9h_B    
                                     !        ! 
  ----SGAAKGSGYGST--RTQG------   L   !        !         +3zkc_A    
                                     !        +---------4 
  ----AT--QAAT--SA------------     --7                  ! +4z5h_A    
                                     !                  +-2 
  ----STKCQAAT--SA------------   L   !                    +3dnv_B    
                                     ! 
  ------SGKGSCQTSTRG----------   L   +-------------------6w1a_A    
                                   

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updated Tue Dec 19 06:56:08 2023