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legend  pdf

structure nameCRYSTAL STRUCTURE OF A DIMER OF N-TERMINAL DOMAINS OF AHRC IN COMPLEX WITH AN 18BP DNA OPERATOR SITE
(Arginine repressor)
referencePhillips et al. J.Mol.Biol. 379 284 2008
sourceBacillus subtilis
experimentX-ray (resolution=2.85, R-factor=0.208)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyArginine repressor, DNA binding domain;
multimeric complexes2p5l_DH
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureMTQASR

Estimated binding specificities ?

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# IC=5.379 IC/col=0.896 n_of_columns=6 specificity:   
A |   9   0  96  67   0   9
C |   9   0   0   9   0   9
G |   9  96   0   9   0   9
T |  69   0   0  11  96  69
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: AHRC
CATGAATAAAAATGPubMed2p5l_D(2.61e-04)

Dendrogram of similar interfaces ?

matrix format
  
  ------------NAST--RGHTNTST--------   L                            +-----------------------------7fj2_B    
                                                                  +-5 
  ----------------NASTHT--ST--------                            +-6 +-----------------------------3co7_C    
                                                                ! ! 
  ------YA----YTRG------------------   L                        ! +-----------------------------4mtd_D    
                                                                ! 
  ----DT----RGRCTT----KT----------RT   L                      +-7                      +------2o9l_A    
                                                              ! !  +-------------------1 
  RT--LT--NTHGTA----YT--------------                          ! !  !                   +------2efw_A    
                                                              ! +--4 
  ----LT--RT--YTPT------------------   L                      !    !            +-------------6qil_A    
                                                            +-8    !  +---------2 
  ----RC----------------------------                        ! !    +--3         +-------------7cow_T    
                                                            ! !       ! 
  ------------TTHT------------------   L                  +-9 !       +-----------------------7b0c_A    
                                                          ! ! ! 
  --RC------------------------------                      ! ! +-----------------------------6l9z_S    
                                                       +-10 ! 
  ------------------NAHT------------   L               !  ! +-----------------------------7cby_C    
                                                    +-11  !  
  --------STRGQTQA--ST--------------   L            !  !  +-----------------------------7t8k_B    
                                                 +-12  !  
  --------------------YGRG----------             !  !  +-----------------------------4wcg_A    
                                              +-13  !  
  ------------------RTVA--ITNAMCRG--   L      !  !  +-----------------------------1yrn_A    
                                           +-14  !  
  --------------------IT--QCNAACRG--   L   !  !  +-----------------------------6a8r_A    
                                         -15  !  
  ----------STVC----KGDC--RG--------   L   !  +-----------------------------1w0t_A    
                                           !  
  --------------------VA--QTNA------   L   +-----------------------------5hod_A    
                                         

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updated Tue Dec 19 06:49:17 2023