interface graph thumbnail
legend  pdf

structure nameMETAL-DEPLETED ECL18KI IN COMPLEX WITH UNCLEAVED, MODIFIED DNA
(R.ECL18KI)
referenceSzczepanowski et al.
sourceENTEROBACTER CLOACAE
experimentX-ray (resolution=1.70, R-factor=0.208)
structural superfamilyRestriction endonuclease-like;
sequence familyEcoRII C terminal;
multimeric complexes2fqz_AB 2fqz_CD 2gb7_AB 2gb7_CD
redundant complexes2fqz_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQRSTRER

Estimated binding specificities ?

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# IC=4.907 IC/col=0.981 n_of_columns=5 specificity:   
A |  23   8   0   0   0
C |  10  77  96   0   0
G |  55   2   0  96  95
T |   8   9   0   0   1
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: ECL18KI
CCGGCPubMed2gb7_A(3.63e-08), 2fqz_AB(3.54e-04), 2fqz_CD(3.54e-04), ... (total=6)
GCCGGCPubMed2gb7_A(1.67e-07), 2fqz_AB(1.12e-03), 2fqz_CD(1.12e-03), ... (total=6)

Dendrogram of similar interfaces ?

matrix format
  
  RA--CAWA----QG--RCSG--AAEATGRGECRG----   L                  +-------------2gb7_A    
                                                 +------------1 
  --RA--EAYAFA--RAKCSCRAAASA--KGDGRG----   L   +-2            +-------------3hqg_A    
                                               ! ! 
  --------------------------------ET----     --3 +--------------------------6g3b_A    
                                               ! 
  ----------------EAKT--------NA--KGDCKA   L   +---------------------------3wvk_C    
                                             

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updated Tue Dec 19 06:29:08 2023