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3D-footprint cannot reliably estimate the specificity of proteins that bind to single-stranded DNA molecules, as these often accumulate many base contacts which distort the calculations.


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updated Tue Dec 19 06:23:34 2023
structure nameCRYSTAL STRUCTURE OF THE HUMAN TRANSCRIPTION COFACTOR PC4 IN COMPLEX WITH SINGLE-STRANDED DNA
(ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15)
referenceWerten et al. Nat.Struct.Mol.Biol. 13 181 2006
sourceHOMO SAPIENS
experimentX-ray (resolution=1.74, R-factor=0.229)
structural superfamilyssDNA-binding transcriptional regulator domain;
sequence familyTranscriptional Coactivator p15 PC4;
multimeric complexes2c62_AB 4usg_AB
redundant complexes4usg_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence