1u8b_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE METHYLATED N-ADA/DNA COMPLEX (Ada polyprotein)
reference	Norman et al. Mol.Cell 20 117 2005
source	Escherichia coli
experiment	X-ray (resolution=2.10, R-factor=0.235)
structural superfamily	Ada DNA repair protein, N-terminal domain N-Ada 10;
sequence family	Metal binding domain of Ada; Bacterial regulatory helixturnhelix;
redundant complexes	1zgw
reference complex	1zgw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1u8b_A interface=27,28,38,64,107, mkddqrwqsvlardpnadgefvfavrTTgifrpscraRhalrenvsfyanasealaagfrpckRcqpdkanprqhrldkithacrlleqetpvtlealadqvamspFhlhrlfkattgmtpkawqqawrar
interface signature	TTRRF

Estimated binding specificities ?

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# IC=4.778 IC/col=0.531 n_of_columns=9

specificity:

A |  90   0  18   6  54  24  24  24   0
C |   6   6  24   0  12  24  24  24   0
G |   0   0  12   6  12  24  24  24   0
T |   0  90  42  84  18  24  24  24  96

scan!

Dendrogram of similar interfaces ?

matrix format

  
  TTTTRTRT----FT------   L              +----------------1u8b_A    
                                 +------1 
  --------DTRTRGTTKT--   L     +-2      +----------------2o8k_A    
                               ! ! 
  ------------------YG       +-3 +-----------------------1sfu_A    
                             ! ! 
  ----------------RGYG     --4 +-------------------------1qbj_C    
                             ! 
  ------------------YG       +--------------------------3irr_C

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updated Mon Dec 18 06:11:39 2023