interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF C/EBPALPHA-DNA COMPLEX
(CCAATenhancer binding protein alpha)
referenceSebastian et al. J.Biol.Chem. 278 15178 2003
sourceRattus norvegicus
experimentX-ray (resolution=2.80, R-factor=0.221)
structural superfamilyLeucine zipper domain;
sequence familyBasic region leucine zipper;
multimeric complexes1nwq_AC
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNAVSR

Estimated binding specificities ?

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# IC=2.960 IC/col=0.740 n_of_columns=4 specificity:   
A |   7   3   4   5
C |   6  10   5  80
G |   6   0  77   7
T |  77  83  10   4
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: EBPALPHA
CGCAAPubMed1nwq_C(1.41e-04), 1nwq_AC(1.71e-06)

Dendrogram of similar interfaces ?

matrix format
  
  ------RA----NT--AAVT----STRG----   L                        +-1hjb_A    
                                                +-------------3 
  ------NCRT--ATAT--STRG----------          +---5             +-1t2k_D    
                                            !   ! 
  RGNC----YGAT----RC--------------   L      !   +---------------4eot_A    
                                            ! 
  ----------------NT----ATAT--STRG   L   +--6                  +1dh3_C    
                                         !  !        +---------2 
  ------------NC--AT------STRA----       !  !        !         ! +1a02_J    
                                         !  +--------4         +-1 
  --------FTRC--------------------   L --7           !           +7aw7_D    
                                         !           ! 
  ------------NCTT--AT------RG----   L   !           +----------2dgc_A    
                                         ! 
  ----RG------NC--YGAT----CTRG----   L   +----------------------2wt7_B    
                                       

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updated Tue Dec 19 05:58:28 2023