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legend  pdf

structure nameCRYSTAL STRUCTURE OF THE MATA1/MATALPHA2-3A HETERODIMER BOUND TO DNA COMPLEX
(Mating-type protein alpha-2)
referenceMathias et al. Structure 10 961 2002
sourceSaccharomyces cerevisiae
experimentX-ray (resolution=2.30, R-factor=?)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes1akh_AB 1apl_CD 1le8_AB 1yrn_AB
redundant complexes1apl_D 1akh 1yrn
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHRNAAA

Estimated binding specificities ?

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# IC=3.766 IC/col=0.628 n_of_columns=6 specificity:   
A |   8  48  24   0  64   0
C |   8   8  24   0  16  96
G |   0  16  24   8   8   0
T |  80  24  24  88   8   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ------------------------NCITNARGRG--   L                            +6fqq_E    
                                                                +-----1 
  RT----------------------NT--NAITRG--   L      +---------------7     +5zjt_B    
                                                !               ! 
  ----------NT------------------------       +-12               +-----7tve_F    
                                             !  !  
  RA----------------------ITQTNAMG----   L   !  +---------------------5zjt_E    
                                             !  
  RT----------------------NT--NA--RG--   L   !                       +1b8i_B    
                                             !                   +---2 
  RT----------------------NT--NAIARG--   L   !                +--6   +1b72_B    
                                             !                !  ! 
  RA--------------------KGSAQA--------   L   !                !  +---6j5b_C    
                                           -13           +----8 
  RT----------------------IAKGNA------   L   !           !    !        +2hdd_A    
                                             !           !    !      +-3 
  RT--------------------KTIAQCNA----RT   L   !           !    +------4 +1ig7_A    
                                             !      +----9           ! 
  --------------YTVC----KGDCKC--------   L   !      !    !           +2qhb_A    
                                             !      !    ! 
  ------------------------IA--NA------       !   +-10    !          +4qtr_D    
                                             !   !  !    +----------5 
  RT----------------------ITQCNAACRG--   L   !   !  !               +6a8r_A    
                                             +--11  !  
  RA------YA--------------IAQCNAYCKG--   L       !  +----------------5flv_I    
                                                 !  
  --NGRGTG----LG----LCRG--------------           +------------------4e9f_A    
                                           

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updated Tue Dec 19 05:52:44 2023