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structure name3D SOLUTION NMR STRUCTURE OF THE M9I MUTANT OF THE HMG-BOX DOMAIN OF THE HUMAN MALE SEX DETERMINING FACTOR SRY COMPLEXED TO DNA
(SEX-DETERMINING REGION Y PROTEIN)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyHMG-box;
sequence familyHMG high mobility group box;
redundant complexes1j46
reference complex1hry_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNFIRNSSYPR

Estimated binding specificities ?

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# IC=4.732 IC/col=0.789 n_of_columns=6 specificity:   
A |  76   6  76  78  89   6
C |   6  76   6   6   7  89
G |   8   6   8   6   0   1
T |   6   8   6   6   0   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: SRY
AACAATPubMed1j47_A(1.13e-03), 1j46_A(3.39e-03)
AACAAAGPubMed1j47_A(6.45e-06), 1j46_A(5.20e-05)
TCAAAGPubMed1j47_A(1.14e-03), 1j46_A(3.39e-03)
ACAATPubMed1j47_A(3.57e-04), 1j46_A(1.01e-03)
ATTGTTPubMed1j47_A(1.13e-03), 1j46_A(3.39e-03)
CTTTGPubMed1j47_A(3.63e-04), 1j46_A(1.01e-03)
GAACAATPubMed1j47_A(3.39e-03), 1j46_A(1.05e-02)
NACAATPubMed1j47_A(1.13e-03), 1j46_A(3.39e-03)

Dendrogram of similar interfaces ?

matrix format



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updated Mon Dec 18 05:12:57 2023