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structure nameCRYSTAL STRUCTURE OF CENP-B(1-129) COMPLEXED WITH THE CENP-B BOX DNA
(MAJOR CENTROMERE AUTOANTIGEN B)
referenceRIKEN Structural Genomics/Proteomics Initiative (RSGI)
sourceHOMO SAPIENS
experimentX-ray (resolution=2.50, R-factor=0.222)
structural superfamilyHomeodomain-like;
sequence familyCENPB Nterminal DNAbinding domain; Centromere binding protein B, DNA bind;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRQPSTSTTKSNDR

Estimated binding specificities ?

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# IC=12.498 IC/col=0.893 n_of_columns=14 specificity:   
A |   0   0   4   0   7  24  79  62  24   0   0   4   0  91
C |  96   0   4   0   4  24   4  16  24  96   0   4   0   0
G |   0  96   2   0  76  24   4   9  24   0  96  79  96   0
T |   0   0  86  96   9  24   9   9  24   0   0   9   0   5
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: CENP-B
CTTCGTTGGAAACGGGAPubMed1hlv_A(1.11e-16)
CTTCGTTGGAAACGGGTPubMed1hlv_A(6.32e-13)
TCCCGTTTCCAACGAAGPubMed1hlv_A(1.11e-16)
TCCCGTTTCCAPubMed1hlv_A(1.87e-10)

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updated Mon Dec 18 05:10:02 2023