structure name | DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL AND DTXR CONSENSUS BINDING SEQUENCE (DIPHTHERIA TOXIN REPRESSOR) |
reference | Murphy et al. Biochemistry 39 10397 2000 |
source | Corynebacterium diphtheriae |
experiment | X-ray (resolution=3.00, R-factor=0.245) |
structural superfamily | "Winged helix" DNA-binding domain;Iron-dependent repressor protein, dimerization domain; |
sequence family | Iron dependent repressor, Nterminal D; Iron dependent repressor, metal bindin; MarR family; |
multimeric complexes | 1f5t_ABCD |
links to other resources | NAKB PDIdb DNAproDB |
protein sequence | |
interface signature | SPTQR |
Estimated binding specificities ?
contact |
A | 11 0 9 9 C | 9 0 67 9 G | 67 96 11 11 T | 9 0 9 67scan! |
Related DNA sequences reported in the literature ?
site | source | matches (E-value) |
---|---|---|
term: DTXR | ||
TTAGGTGAGACGCACCCAT | PubMed | 1f5t_ABCD(1.22e-03) |
Dendrogram of similar interfaces ?
matrix formatRGRTKG------------------------YGKC L +-----------------------------6lui_A ! ------------------------YG-------- ! +2heo_D ! +---------1 ------LT------RTSGTGQTRG---------- L ! +-----2 +2xro_E +-6 ! ! ----------------TTHT--KG----RC---- L ! ! +---3 +---------7b0c_A ! ! ! ! --------SGQG--YCNC---------------- ! ! +---4 +---------------2ve9_C --7 ! ! ! --------TC--STKTPTTTFT--------RT-- ! +-----5 +-------------------4ass_H ! ! ------------DCLT--AGTTRG--RG------ L ! +-----------------------5h3r_A ! ------------------------------RT-- +-----------------------------3gfi_A |
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updated Tue Dec 19 05:37:29 2023