interface graph thumbnail
legend  pdf

structure nameDIPHTHERIA TOX REPRESSOR (C102D MUTANT)/TOX DNA OPERATOR COMPLEX
(DIPHTHERIA TOX REPRESSOR)
referenceVanderspek et al.
sourceCorynebacterium diphtheriae
experimentX-ray (resolution=3.00, R-factor=?)
structural superfamilyIron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;
sequence familyIron dependent repressor, Nterminal D; Iron dependent repressor, metal bindin; MarR family;
multimeric complexes1c0w_ABCD 1ddn_ABCD
redundant complexes1c0w_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSPTSQR

Estimated binding specificities ?

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# IC=4.915 IC/col=0.819 n_of_columns=6 specificity:   
A |   7   7  96   7   0   7
C |   9   7   0   7   0   7
G |   7   9   0  73  96   9
T |  73  73   0   9   0  73
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: TOX REPRESSOR
ACAATTAGGPubMed1ddn_B(3.90e-05), 1c0w_D(3.90e-06)
ATAATTAGGPubMed1ddn_B(3.90e-05), 1c0w_D(3.90e-06)

Dendrogram of similar interfaces ?

matrix format
  
  ------------ST--PTTCSTQC------RA--------   L                                   +1ddn_B    
                                                           +---------------------1 
  ------------ST--PTTC--QG------RG--------   L             !                     +1f5t_A    
                                                           ! 
  ----------------------------YG----------                 !                      +2heo_D    
                                                         +-6                 +----2 
  ------LT------RTSGTGQTRG----------------   L           ! !      +----------3    +2xro_E    
                                                         ! !      !          ! 
  ----------------TTHT--KG----------RC----   L           ! ! +----4          +----7b0c_A    
                                                     +---7 ! !    ! 
  --------SGQG--YCNC----------------------           !   ! +-5    +---------------2ve9_C    
                                                     !   !   ! 
  --------TC--STKTPTTTFT------------------         +-8   !   +--------------------4ass_H    
                                                   ! !   ! 
  ------------DCLT--AGTTRG------RG--------   L     ! !   +-----------------------5h3r_A    
                                                 +-9 ! 
  RGRTKG------------------------------YGKC   L   ! ! +---------------------------6lui_A    
                                               -10 ! 
  --------------------NAST--RGHT--ST------   L   ! +----------------------------3g73_A    
                                                 !  
  ------------------KT--RGAT--RGYA--------   L   +----------------------------4iri_A    
                                               

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updated Tue Dec 19 05:31:32 2023