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legend  pdf

structure nameEBNA-1 NUCLEAR PROTEIN/DNA COMPLEX
(PROTEIN NUCLEAR PROTEIN EBNA1)
referenceBochkareva et al.
sourceHuman herpesvirus 4
experimentX-ray (resolution=2.20, R-factor=0.208)
structural superfamilyViral DNA-binding domain;
sequence familyEpstein Barr virus nuclear antigen1, DNAbi;
multimeric complexes1b3t_AB 6pw2_ABCD 6pw2_IKL 7u1t_ABCD 8dlf_ABCD
redundant complexes6pw2
reference complex7u1t_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKWFRNKFKTYNR

Estimated binding specificities ?

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# IC=6.292 IC/col=0.899 n_of_columns=7 specificity:   
A |   9   0   0  96  75   7   9
C |   7   0   0   0   7   9  73
G |  73  96  96   0   7  73   7
T |   7   0   0   0   7   7   7
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Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: EBNA-1
TAGCATATGCTAPubMed1b3t_AB(1.85e-11), 6pw2_IJKL(1.59e-09)

Dendrogram of similar interfaces ?

matrix format
  
  WCFT----KG--KGTAYCNGRT--   L                             +5t7x_B    
                                        +------------------1 
  WGFTRTNTKGFTKTTGYCNGRT--   L   +------3                  +1b3t_A    
                                 !      ! 
  --------KG--------------   L --4      +------------------4uzb_B    
                                 ! 
  ----------------KGCGFT--   L   !             +-----------2bop_A    
                                 +-------------2 
  ----------------------RC   L                 +-----------2itl_B    
                               

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updated Mon Dec 18 04:57:10 2023